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Explore career opportunities with Marinus.

Marinus is comprised of a team of talented professionals committed to developing new therapies for CNS disorders and passionate about making a positive difference in the lives of the patients we serve.



As our business expands, we are creating new positions to support and enable growth and looking for highly-energetic, self-motivated leaders that are seeking a fulfilling career to complement our experienced team.

If you possess these qualities and seek the opportunity to work in an entrepreneurial environment with a chance to make a difference and help patients, email your credentials today.

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Join Our Team

The following positions are currently open at Marinus Pharmaceuticals. If interested in a position, please send your resume to This email address is being protected from spambots. You need JavaScript enabled to view it..

  • Clinical Trial Manager


    Manages the operational aspects of assigned clinical trials, including liaising with investigational sites, conducting on-site monitoring and/or co-monitoring visits, and managing internal and external vendors/disciplines Clinical Research Organizations.

    Develops study specific tools and documents and provides overall direction for the clinical sites and study team members. Ensures that clinical trials are conducted according to the study protocol and in compliance with all applicable SOPs and regulatory guidelines.

    Recommends and implements innovative process ideas to positively impact clinical trials management. Possesses the ability to work efficiently in a fast-paced virtual environment.

    Qualifications/Experience:

    • Bachelor’s degree required
       
    • 3-5 years pharmaceutical industry clinical trial management experience, phase 1-3 trials
       
    • Experience with CNS clinical trials preferred
       
    • Travel requirements: variable: ~25%
       

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    Primary Responsibilities and Duties:

    • Conducts and/or oversees all aspects required for selecting, initiating, monitoring and closing investigational sites in accordance with all applicable SOPs and GCP/ICH requirements.
       
    • Serves as a primary contact for internal clinical monitoring study team members, external vendors and clinical sites.
       
    • Leads weekly conference calls
       
    • Manages and executes project management (maintains integrated timelines with all discipline deliverables), monitoring, site management, trial master files, and clinical research associate performance.
       
    • Assists in the preparation of clinical trial documents, including study protocols, amendments, model ICFs, laboratory manuals, CRF completion guidelines, study specific instructions, etc.
       
    • Provides timely and accurate information to Management for project level tracking.
       
    • Participates in evaluating investigational drug (IP) supply requirements and manages the logistical aspects of distributing supplies to the investigational sites.
       
    • Coordinates investigator meetings and develops presentation materials.
       
    • Conducts weekly team (interdisciplinary) meetings.
       
    • Manages CRAs and CTAs
       
    • Routinely reviews study data and progress of EDC entry; works with data management and clinical sites to resolve data discrepancies. This includes reviewing primary, secondary and safety endpoints for inconsistency, irregularities, and/or signals.
       
    • Identifies program/clinical trial risks; proactively suggests and implements mitigation strategies.
       
    • Participates in the management of vendors to get deliverables delivered on-time and on-budget.
       
    • Participates in the preparation and finalization of company SOPs as necessary.
       
    • Performs job duties with minimal supervision and has a sound critical thinking and problem-solving skills.
       




  • Sr. Clinical Trial Manager/Clinical Trial Manager


    Position Summary:

    Manages the operational aspects of assigned clinical trials, including liaising with investigational sites, conducting on-site monitoring and/or co-monitoring visits, and managing internal and external vendors/disciplines Clinical Research Organizations.

    Develops study specific tools and documents and provides overall direction for the clinical sites and study team members. Ensures that clinical trials are conducted according to the study protocol and in compliance with all applicable SOPs and regulatory guidelines.

    Recommends and implements innovative process ideas to positively impact clinical trials management. Possesses the ability to work efficiently in a fast-paced virtual environment.

    Qualifications/Experience:

    • Bachelor’s degree required
       
    • 3-5 years pharmaceutical industry clinical trial management experience, phase 1-3
       
    • Experience with CNS clinical trials preferred
       
    • Travel requirements: 25%
       

    This email address is being protected from spambots. You need JavaScript enabled to view it.

    Primary Responsibilities and Duties:

    • Conducts and/or oversees all aspects required for selecting, initiating, monitoring and closing investigational sites in accordance with all applicable SOPs and GCP/ICH requirements.
       
    • Serves as a primary contact for internal clinical monitoring study team members, external vendors and clinical sites. 
       
    • Leads weekly conference calls
       
    • Manages and executes project management (maintains integrated timelines with all discipline deliverables), monitoring, site management, trial master files, and clinical research associate performance.
       
    • Assists in the preparation of clinical trial documents, including study protocols, amendments, model ICFs, laboratory manuals, CRF completion guidelines, study specific instructions, etc.
       
    • Provides timely and accurate information to Management for project level tracking. 
       
    • Participates in evaluating investigational drug (IP) supply requirements and manages the logistical aspects of distributing supplies to the investigational sites
       
    • Coordinates investigator meetings and develops presentation materials.
       
    • Conducts weekly team (interdisciplinary) meetings.
       
    • Manages CRAs and CTAs
       
    • Routinely reviews study data and progress of EDC entry; works with data management and clinical sites to resolve data discrepancies. This includes reviewing primary, secondary and safety endpoints for inconsistency, irregularities, and/or signals.
       
    • Identifies program/clinical trial risks; proactively suggests and implements mitigation strategies.
       
    • Participates in the management of vendors to get deliverables delivered on-time and on-budget.
       
    • Participates in the preparation and finalization of company SOPs as necessary.
       
    • Performs job duties with minimal supervision and has a sound critical thinking and problem-solving skills.
       




  • Clinical Program Director


    Provides leadership, project management, and program oversight to plan and conduct multiple, high quality global clinical trials concurrently.  The incumbent will manage all operational aspects of clinical development projects. Open effective, and proactive communication of the clinical development activities is critical for success in this role.
    Must have strong leadership skills and be able to work independently and productively.

    Responsibilities

    • Proactively manage all operational aspects of the clinical trials within assigned global programs including but not limited to management of trial timeline, budget, resources and vendors.
       
    • Represent Clinical Operations Project Team meetings providing updates including status of trial-level activities, program initiatives, etc.
       
    • Coordinate trial activities, vendors, sites and CROs; build and maintain effective working relationships with interfacing groups.
       
    • Ensure effective project plans are in place and operational for each trial and work proactively with the clinical trial team members (both internal and external) to set priorities, operational procedures, policies, guidelines and regulatory requirements.
       
    • Ensure study risks are appropriately escalated to the Executive Director of Clinical Development and Operations.
       
    • Monitor the quality of vendor deliverables, address quality issues and identify opportunities to improve training, execution and data flow across all trials within assigned program.
       
    • Review and approve vendor invoices in collaboration with Accounting team to ensure payments are issued in a timely manner based on levels of authority.
       
    • Ensure all project level study documentation is filed in the TMF in accordance with company SOPs/all regulatory requirements.
       
    • Foster and cultivate relationships with key opinion leaders and other experts in the CNS community.
       
    • Chair and lead clinical trial team meetings and ensure meeting minutes are completed, distributed to team members and filed in a timely manner.
       
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    Skills, Education, and Experience Required
    • BS in the life sciences or related discipline, at minimum
       
    • 10+ years of clinical operations experience, with increasing levels of responsibility,
       
    • A minimum of three years’ experience of current clinical project director experience leading trial teams.
       
    • Therapeutic experience in depression or epilepsy -- seizure related therapeutic area
       
    • Experience in global Phase III trials 
       
    • Experience in managing global clinical trials
       
    • Ability to work both independently and as part of a team demonstrating excellent communication and interpersonal skills is required.
       
    • Excellent working knowledge of FDA, GCP and ICH guidelines
       
    • Experience working with foreign regulatory agencies (e.g. EMA), preferred
       


 
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Explore the Benefits

Marinus is committed to a culturally diverse workforce, and offers employees an attractive package of compensation and benefits, including:

  • Short Term Disability
     
  • Long Term Disability
     
  • Paid Holidays
     
  • 401(k) Savings and Investment Plan
  • Health Insurance
     
  • Dental Insurance
     
  • Life and AD&D Insurance
     
  • Equity Compensation
     
CDKL5 Child 1

Our goal at Marinus is to improve the lives of patients and families who suffer from neuropsychiatric disorders. Ganaxolone utilizes an endogenous mechanism of action to modulate the GABAA system in the brain.