Careers Center

Explore career opportunities with Marinus.

Marinus is comprised of a team of talented professionals committed to developing new therapies for CNS disorders and passionate about making a positive difference in the lives of the patients we serve.

As our business expands, we are creating new positions to support and enable growth and looking for highly-energetic, self-motivated leaders that are seeking a fulfilling career to complement our experienced team.

If you possess these qualities and seek the opportunity to work in an entrepreneurial environment with a chance to make a difference and help patients, email your credentials today.

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Join Our Team

The following positions are currently open at Marinus Pharmaceuticals. If interested in a position, please send your resume to

Clinical Trial Manager

Manages the operational aspects of assigned clinical trials, including liaising with investigational sites, conducting on-site monitoring and/or co-monitoring visits, and managing internal and external vendors/disciplines Clinical Research Organizations.

Develops study specific tools and documents and provides overall direction for the clinical sites and study team members. Ensures that clinical trials are conducted according to the study protocol and in compliance with all applicable SOPs and regulatory guidelines.

Recommends and implements innovative process ideas to positively impact clinical trials management. Possesses the ability to work efficiently in a fast-paced virtual environment.


  • Bachelor’s degree required
  • 3-5 years pharmaceutical industry clinical trial management experience, phase 1-3 trials
  • Experience with CNS clinical trials preferred
  • Travel requirements: variable: ~25%

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Primary Responsibilities and Duties:

  • Conducts and/or oversees all aspects required for selecting, initiating, monitoring and closing investigational sites in accordance with all applicable SOPs and GCP/ICH requirements.
  • Serves as a primary contact for internal clinical monitoring study team members, external vendors and clinical sites.
  • Leads weekly conference calls
  • Manages and executes project management (maintains integrated timelines with all discipline deliverables), monitoring, site management, trial master files, and clinical research associate performance.
  • Assists in the preparation of clinical trial documents, including study protocols, amendments, model ICFs, laboratory manuals, CRF completion guidelines, study specific instructions, etc.
  • Provides timely and accurate information to Management for project level tracking.
  • Participates in evaluating investigational drug (IP) supply requirements and manages the logistical aspects of distributing supplies to the investigational sites.
  • Coordinates investigator meetings and develops presentation materials.
  • Conducts weekly team (interdisciplinary) meetings.
  • Manages CRAs and CTAs
  • Routinely reviews study data and progress of EDC entry; works with data management and clinical sites to resolve data discrepancies. This includes reviewing primary, secondary and safety endpoints for inconsistency, irregularities, and/or signals.
  • Identifies program/clinical trial risks; proactively suggests and implements mitigation strategies.
  • Participates in the management of vendors to get deliverables delivered on-time and on-budget.
  • Participates in the preparation and finalization of company SOPs as necessary.
  • Performs job duties with minimal supervision and has a sound critical thinking and problem-solving skills.

Clinical Trial Associate

Clinical Trial Associate (CTA) operates as the central contact for the clinical study team on designated projects. Assist the clinical study team members with accurately updating and maintaining the clinical systems that track site compliance and performance within project timelines. Participate in the preparation, handling, distribution, review and archiving of clinical documentation and reports; as well as the distribution and tracking of clinical trial supplies. Aids in the planning, conduct, management, and completion of clinical studies through interaction with sites, vendors, sponsors, and team members. and their associated communications and documentation. Assist with accurately updating and maintaining clinical systems; track site compliance and performance within project timelines. Participate in the preparation, handling, distribution, review and archiving of clinical documentation and reports; as well as the distribution and tracking of clinical trial supplies. Interaction with sites, vendors, sponsors, and team members.


  • BS or BA required
  • 1-3 years demonstrated experience supporting clinical trial operations involving multiple projects

Key Skills

  • General knowledge of pharmaceutical research industry
  • Ability to think critically, identify root causes, and formulate potential solutions proactively
  • Well organized and capable of managing multiple tasks with respect to priorities.
  • Excellent verbal and written skills
  • Ability to deal effectively with all levels of management
  • Able to resolve conflicts in a diplomatic manner
  • Solid grasp of MS PowerPoint, Word, Excel and Project
  • Can locate information quickly and resourcefully
  • Self-motivated and able to function with little supervision
  • Highly detail-oriented
  • Strong team member

Apply Now

Primary Responsibilities and Duties:

  • Assist with documents during study start-up including CDAs and CTAs
  • Assist with compilation of regulatory documents
  • Track incoming and outgoing regulatory packages
  • Assist in organization of Investigators’ Meetings
  • Assist with patient tracking to document patient visits and overall study progress
  • File essential documents and maintain the TMF
  • Track CRFs
  • Coordinate investigator payments for studies where the Sponsor is responsible for this activity. Verify investigator payment details submitted for payment by CROs for studies where CROs are responsible for this activity
  • Support Clinical department and/or specific CTM with meetings, including preparation of agendas and minutes and tracking action items
  • Distribute trial-related materials to study sites
  • Support preparation and subsequent distribution of newsletters
  • Prepare Study File Notebook for review by study team
  • Create and maintain tracking tools to monitor collection and expiry of essential documents; work with CRO team to obtain required updates
  • Review study files/TMF periodically for accuracy and completeness
  • Assist with essential document reconciliation at study end
  • Assists with tracking study metrics including patient screening and enrollment, data entry, query resolution, etc. optimize the vendor reporting
  • Provides administrative support for study team members including courier shipments, photocopying, telephone coverage, organization of meetings and teleconferences, generation of meeting minutes
  • As directed by Clinical Trial Manager, may directly facilitate resolution of study related issues through communication with investigator site personnel, clinical trial vendors including central laboratories, CROs, etc.
  • May assist Clinical Trial Manager in coordination of payments to clinical sites and vendors


career benefits


Explore the Benefits

Marinus is committed to a culturally diverse workforce, and offers employees an attractive package of compensation and benefits, including:

  • Health Insurance
  • Dental Insurance
  • Life and AD&D Insurance
  • Equity Compensation
  • Short Term Disability
  • Long Term Disability
  • Paid Holidays
  • 401(k) Savings and Investment Plan

chris cashman with patient

“Our goal at Marinus is to maximize the value of ganaxolone – a positive allosteric modulator of GABAA – with a new mechanism of action and various dose forms to maximize therapeutic reach to adults and children in both acute and chronic care settings.”

Christopher M. Cashman, CEO

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Find helpful information and patient networks, as well as clinical trial opportunities.

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science & pipeline

About the Science

See how ganaxolone works as a new mechanism of action.

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